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Cpetm1Yplo
Targeted Allele Detail
Nomenclature
Symbol: Cpetm1Yplo
Name: carboxypeptidase E; targeted mutation 1, Y Peng Loh
MGI ID: MGI:3527901
Synonyms: CPE KO
Gene: Cpe  Location: Chr8:64592542-64693054 bp, - strand  Genetic Position: Chr8, 32.3 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95741
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 4 and 5 were deleted via Cre-mediated excision. Western blot of pituitary from mutants confirmed the lack of protein. (J:95741)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cpe Mutation:  19 strains or lines available
References
Original:  J:95741 Cawley NX, et al., The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits. Endocrinology. 2004 Dec;145(12):5807-19
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory