About   Help   FAQ
Homer2tm1Mhd
Targeted Allele Detail
Nomenclature
Symbol: Homer2tm1Mhd
Name: homer scaffolding protein 2; targeted mutation 1, Marlin H Dehoff
MGI ID: MGI:3526530
Synonyms: H2ko
Gene: Homer2  Location: Chr7:81609730-81707527 bp, - strand  Genetic Position: Chr7, 45.71 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95213
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA PGK-neomycin gene was inserted in inverse orientation into exon 3. mRNA and protein products could not be detected. (J:95213)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Homer2 Mutation:  12 strains or lines available
References
Original:  J:95213 Shin DM, et al., Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCbeta GAP activities. J Cell Biol. 2003 Jul 21;162(2):293-303
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/19/2017
MGI 6.10
The Jackson Laboratory