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Homer2tm1Mhd
Targeted Allele Detail
Nomenclature
Symbol: Homer2tm1Mhd
Name: homer scaffolding protein 2; targeted mutation 1, Marlin H Dehoff
MGI ID: MGI:3526530
Synonyms: H2ko
Gene: Homer2  Location: Chr7:81609730-81707527 bp, - strand  Genetic Position: Chr7, 45.71 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95213
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA PGK-neomycin gene was inserted in inverse orientation into exon 3. mRNA and protein products could not be detected. (J:95213)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Homer2 Mutation:  10 strains or lines available
References
Original:  J:95213 Shin DM, et al., Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCbeta GAP activities. J Cell Biol. 2003 Jul 21;162(2):293-303
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory