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Targeted Allele Detail
Symbol: Xirp1tm1Jl
Name: xin actin-binding repeat containing 1; targeted mutation 1, Jim Lin
MGI ID: MGI:3521795
Synonyms: mXinalpha
Gene: Xirp1  Location: Chr9:120013755-120023598 bp, - strand  Genetic Position: Chr9, 71.36 cM
Germline Transmission:  Earliest citation of germline transmission: J:112201
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsNeo-LacZ cassette was inserted into ATG initiation codon to disrupt the coding frame. The targeting vector contains a mutation to change ATG to ATC and a replacement of 203 bp downstream of ATG with the LacZ-Neo resistance cassette. Northern and Western blot analysis confirmed the absence of transcription and translation. (J:112201, J:132079)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Xirp1 Mutation:  25 strains or lines available
Original:  J:112201 Jung-Ching Lin J, et al., Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin. J Med Sci. 2005 Oct;25(5):215-222
All:  5 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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