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Nodaltm6Rob
Targeted Allele Detail
Nomenclature
Symbol: Nodaltm6Rob
Name: nodal; targeted mutation 6, Elizabeth J Robertson
MGI ID: MGI:3521719
Synonyms: Nodaldeltaaie
Gene: Nodal  Location: Chr10:61417972-61425338 bp, + strand  Genetic Position: Chr10, 32.21 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94418
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsThe 470 bp minimal AIE regulatory element was deleted upon replacement with a floxed PGK-hygro and its subsequent Cre-mediated excision. (J:94418)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nodal Mutation:  18 strains or lines available
References
Original:  J:94418 Vincent SD, et al., Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements. Mech Dev. 2004 Nov;121(11):1403-15
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory