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Rtn4rtm1Stmr
Targeted Allele Detail
Nomenclature
Symbol: Rtn4rtm1Stmr
Name: reticulon 4 receptor; targeted mutation 1, Stephen M Strittmatter
MGI ID: MGI:3514018
Synonyms: NGR-
Gene: Rtn4r  Location: Chr16:18127642-18152408 bp, + strand  Genetic Position: Chr16, 11.23 cM, cytoband B1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94754
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with a neomycin resistance cassette. Northern and Western blot analysis confirmed the absence of both transcription and translation products. (J:94754)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rtn4r Mutation:  9 strains or lines available
References
Original:  J:94754 Kim JE, et al., Nogo-66 receptor prevents raphespinal and rubrospinal axon regeneration and limits functional recovery from spinal cord injury. Neuron. 2004 Oct 28;44(3):439-51
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory