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Sypl2tm1Hta
Targeted Allele Detail
Nomenclature
Symbol: Sypl2tm1Hta
Name: synaptophysin-like 2; targeted mutation 1, Hiroshi Takeshima
MGI ID: MGI:3513758
Synonyms: MG29m1
Gene: Sypl2  Location: Chr3:108211472-108226648 bp, - strand  Genetic Position: Chr3, 46.87 cM, cytoband F3-H2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59188
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe promoter and the first exon were replaced by a neomycin selection cassette. Northern and western blot analysis were used to demonstrate an absence of transcript and protein encoded by this gene. (J:59188)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sypl2 Mutation:  15 strains or lines available
References
Original:  J:59188 Nishi M, et al., Abnormal features in skeletal muscle from mice lacking mitsugumin29. J Cell Biol. 1999 Dec 27;147(7):1473-80
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/15/2017
MGI 6.10
The Jackson Laboratory