Pde4a^tm1Rdu
Targeted Allele Detail

Summary

• Symbol: Pde4a^tm1Rdu
• Name: phosphodiesterase 4A, cAMP specific; targeted mutation 1, Ronald S Duman
• MGI ID: MGI:3513102
• Gene: Pde4a Location: Chr9:21077010-21124544 bp, + strand Genetic Position: Chr9, 7.73 cM
• Alliance: Pde4a^tm1Rdu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94338
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 12, 13 and 14 flanked by two loxP sites one of which also included with an frt flanked neomycin-resistant (neo) cassette. The frt-flp recombination approach was used to selectively excise the neo cassette. In situ hybridization confirmed the absence of transcription. (J:94338)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pde4a Mutation: 39 strains or lines available

References

• Original: J:94338 NIH Mouse Knockout Inventory, Information obtained from the NIH Mouse Knockout Inventory. MGI Direct Data Submission. 2004
• All: 1 reference(s)