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Nrp1tm2.1Ddg
Targeted Allele Detail
Nomenclature
Symbol: Nrp1tm2.1Ddg
Name: neuropilin 1; targeted mutation 2.1, David D Ginty
MGI ID: MGI:3512103
Synonyms: npn-1-, Nrp1del
Gene: Nrp1  Location: Chr8:128358604-128503363 bp, + strand  Genetic Position: Chr8, 75.78 cM, cytoband E
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93799
Parent Cell Line:  GK129 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe floxed region of Nrp1tm2Ddg containing exon 2 was excised by crossing to mice carrying the Tg(CMV-Cre)1Cgn transgene. (J:93799)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nrp1 Mutation:  49 strains or lines available
References
Original:  J:93799 Gu C, et al., Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev Cell. 2003 Jul;5(1):45-57
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory