Angptl4^tm1Jig
Targeted Allele Detail

Summary

• Symbol: Angptl4^tm1Jig
• Name: angiopoietin-like 4; targeted mutation 1, Jeffrey I Gordon
• MGI ID: MGI:3505565
• Synonyms: Fiaf^-
• Gene: Angptl4 Location: Chr17:33993874-34000549 bp, - strand Genetic Position: Chr17, 17.98 cM
• Alliance: Angptl4^tm1Jig page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93455
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A Betageo cassette replaced exons 1-3. Northern blot of adipocyte RNA confirm the absence of transcript in mutant animals. (J:93455)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Angptl4 Mutation: 31 strains or lines available

References

• Original: J:93455 Backhed F, et al., The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A. 2004 Dec 2;101(44):15718-23
• All: 14 reference(s)