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Tg(IRS1)1Mhep
Transgene Detail
Nomenclature
Symbol: Tg(IRS1)1Mhep
Name: transgene insertion 1, Rolf Carlson
MGI ID: MGI:3056765
Transgene: Tg(IRS1)1Mhep  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(IRS1)1Mhep expresses 1 gene
 
Mutation detailsThe transgene contains the human insulin receptor substrate 1 (IRS1) gene. Mice overexpress human IRS1 in the liver. (J:92999)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:92999 Tanaka S, et al., Biological effects of human insulin receptor substrate-1 overexpression in hepatocytes. Hepatology. 1997 Sep;26(3):598-604
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory