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Crebbptm1.1Ltz
Targeted Allele Detail
Nomenclature
Symbol: Crebbptm1.1Ltz
Name: CREB binding protein; targeted mutation 1.1, Beat Lutz
MGI ID: MGI:3056562
Synonyms: CBPstop523
Gene: Crebbp  Location: Chr16:4081334-4213413 bp, - strand  Genetic Position: Chr16, 2.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:93192
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCre mediated recombination of the flanking loxP sites results in the deletion of exon 2 from Crebbptm1Ltz, generating a stop codon in the open reading frame at the beginning of exon 3. (J:93192)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crebbp Mutation:  20 strains or lines available
References
Original:  J:93192 Zhang Z, et al., Generation of a conditional allele of the CBP gene in mouse. Genesis. 2004 Oct;40(2):82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory