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Hpcatm1Toho
Targeted Allele Detail
Nomenclature
Symbol: Hpcatm1Toho
Name: hippocalcin; targeted mutation 1, Toho University
MGI ID: MGI:3055313
Gene: Hpca  Location: Chr4:129111570-129122036 bp, - strand  Genetic Position: Chr4, 62.88 cM, cytoband D2-D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97752
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neo was inserted into intron 1. Western blot and immunocytochemistry confirmed absence of protein in mutants. (J:97752)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hpca Mutation:  4 strains or lines available
References
Original:  J:97752 Korhonen L, et al., Hippocalcin protects against caspase-12-induced and age-dependent neuronal degeneration. Mol Cell Neurosci. 2005 Jan;28(1):85-95
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory