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Tg(PRG3)9Wlad
Transgene Detail
Nomenclature
Symbol: Tg(PRG3)9Wlad
Name: transgene insertion 9, Wyeth Lederle/Anne Deatly
MGI ID: MGI:3055289
Synonyms: PRG3, TGM-PRG-3
Transgene: Tg(PRG3)9Wlad  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x CBA/J)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(PRG3)9Wlad expresses 1 gene
 
Mutation detailsThis line carries ten copies of the human poliovirus receptor transgene (PVR). The human polio virus receptor is a member of the Igg superfamily. Northern and Western blot analyses detected expression of the transgene at levels three times higher in mice carrying this transgene, compared to levels in transgenic mice carrying a single copy of human PVR. (J:92990)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:92990 Deatly AM, et al., Characterization of mouse lines transgenic with the human poliovirus receptor gene. Microb Pathog. 1998 Jul;25(1):43-54
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory