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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(PRG3)9Wlad
transgene insertion 9, Wyeth Lederle/Anne Deatly
MGI:3055289
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(PRG3)9Wlad/0 involves: C57BL/6J * CBA/J MGI:3835113


Genotype
MGI:3835113
tg1
Allelic
Composition		 Tg(PRG3)9Wlad/0
Genetic
Background		 involves: C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(PRG3)9Wlad mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to Picornaviridae infection ( J:92990 , J:127826 )
• when infected with wild-type III poliovirus mice exhibit paralysis, neuron degeneration, and lethality unlike wild-type mice (J:92990)
• onset of disease following exposure to poliovirus is shorter than in mice expressing Tg(PRG1)18Wlad (J:127826)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory