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Chst2tm1Tmu
Targeted Allele Detail
Nomenclature
Symbol: Chst2tm1Tmu
Name: carbohydrate sulfotransferase 2; targeted mutation 1, Takashi Muramatsu
MGI ID: MGI:3052713
Synonyms: GlcNAc6ST-1, Gn6st-, GST2-
Gene: Chst2  Location: Chr9:95399292-95406722 bp, - strand  Genetic Position: Chr9, 50.11 cM, cytoband E3.2-3.3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92231
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe 3' PAPS binding region in the catalytic domain was replaced with a neomycin resistance gene. Southern blot confirmed recombination and RT-PCR indicated no transcript was detected in mutant organs. (J:92231)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Chst2 Mutation:  6 strains or lines available
References
Original:  J:92231 Uchimura K, et al., N-acetylglucosamine 6-O-sulfotransferase-1 regulates expression of L-selectin ligands and lymphocyte homing. J Biol Chem. 2004 Aug 13;279(33):35001-8
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory