Pank3^Gt(XE030)Byg
Gene trapped Allele Detail

Summary

• Symbol: Pank3^Gt(XE030)Byg
• Name: pantothenate kinase 3; gene trap XE030, BayGenomics
• MGI ID: MGI:3051989
• Synonyms: Pank3^{Gt(pGT1Lxf)1Ucd}
• Gene: Pank3 Location: Chr11:35660322-35682112 bp, + strand Genetic Position: Chr11, 21.96 cM
• Alliance: Pank3^Gt(XE030)Byg page

Mutation origin

• Mutant Cell Line: XE030
• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: The pGt1lxf gene trap vector, which integrated randomly into the first intron - which interrupts the coding sequence within the tenth codon - contains a splice acceptor sequence upstream of a Beta-geo (beta-galactosidase/neomycin phosphotransferase II fusion) reporter gene. Transcription from the endogenous promoter of the trapped gene and splicing of the message yields a fusion mRNA joining exogenous upstream exons to the Beta-geo coding sequence. (J:94077)
• Inheritance: Not Specified
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XE030	CC177965 ; (MGI Seq Detail)	5' RACE	Chr11:35660621-35660773 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  9 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pank3 Mutation: 21 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 2 reference(s)