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Tg(Myh6-cre/Esr1*)1Jmk
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-cre/Esr1*)1Jmk
Name: transgene insertion 1, Jeffery D Molkentin
MGI ID: MGI:3050453
Synonyms: alphaMHC-Cre-Mer-Cre, alpha-MHC-MerCreMer, MCM, mer, mER-CRE-mER, MerCreMer, Tg(Myh6-cre/Esr1)1Jmk
Transgene: Tg(Myh6-cre/Esr1*)1Jmk  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    induced by tamoxifen
Mutation:    Insertion
 
Mutation detailsThis transgene expresses a cre recombinase/ mutant estrogen receptor ligand binding domain fusion protein under the control of a mouse cardiac-specific alpha-myosin heavy chain promoter. Expression was detected in the juvenile and adult heart, but the protein is inactive until induced with tamoxifen. (J:82027)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myh6     Summary of all recombinase alleles driven by Myh6.
 

Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:82027 Sohal DS, et al., Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein. Circ Res. 2001 Jul 6;89(1):20-5
All:  157 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory