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Nell2tm1Mho
Targeted Allele Detail
Nomenclature
Symbol: Nell2tm1Mho
Name: NEL-like 2; targeted mutation 1, Masato Horie
MGI ID: MGI:3043786
Synonyms: NELL2-
Gene: Nell2  Location: Chr15:95219451-95528706 bp, - strand  Genetic Position: Chr15, 49.39 cM, cytoband F1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89818
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons encoding the N-terminal region were replaced with a pMC1-neo cassette via homologous recombination. Northern blot and in situ analysis confirmed the absence of mRNA expression in homozygotes. (J:89818)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nell2 Mutation:  14 strains or lines available
References
Original:  J:89818 Matsuyama S, et al., Enhanced long-term potentiation in vivo in dentate gyrus of NELL2-deficient mice. Neuroreport. 2004 Mar 1;15(3):417-20
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory