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Artm1Verh
Targeted Allele Detail
Summary
Symbol: Artm1Verh
Name: androgen receptor; targeted mutation 1, Guido Verhoeven
MGI ID: MGI:3034098
Synonyms: ARfl, ARflox, ARflox, ARloxP-exon2-loxP
Gene: Ar  Location: ChrX:97192375-97366821 bp, + strand  Genetic Position: ChrX, 42.82 cM
Alliance: Artm1Verh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:88169
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 2 was flanked by single loxP sites in introns 1 and 2. (J:88169)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 42 assay results
3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 13 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ar Mutation:  22 strains or lines available
References
Original:  J:88169 De Gendt K, et al., A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1327-32
All:  98 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory