About   Help   FAQ
Becn1tm1Blev
Targeted Allele Detail
Nomenclature
Symbol: Becn1tm1Blev
Name: beclin 1, autophagy related; targeted mutation 1, Beth Levine
MGI ID: MGI:2683696
Synonyms: Atg6-, beclin 1-
Gene: Becn1  Location: Chr11:101285952-101302286 bp, - strand  Genetic Position: Chr11, 64.58 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86953
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 1 and 2 were replace with a neomycin selection cassette inserted by homologous recombination. (J:86953)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Becn1 Mutation:  17 strains or lines available
References
Original:  J:86953 Qu X, et al., Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest. 2003 Dec;112(12):1809-20
All:  25 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/27/2016
MGI 6.05
The Jackson Laboratory