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Mogtm1Reid
Targeted Allele Detail
Nomenclature
Symbol: Mogtm1Reid
Name: myelin oligodendrocyte glycoprotein; targeted mutation 1, Hugh H Reid
MGI ID: MGI:2683672
Synonyms: MOG-
Gene: Mog  Location: Chr17:37010743-37023398 bp, - strand  Genetic Position: Chr17, 19.16 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86663
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.4 kb genomic fragment, containing the proximal promoter and exon 1, was replaced with a neomycin selection cassette. Protein was undetected by Western blot analysis of homozygous mutant CNS tissue. (J:86663)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mog Mutation:  47 strains or lines available
References
Original:  J:86663 Linares D, et al., The magnitude and encephalogenic potential of autoimmune response to MOG is enhanced in MOG deficient mice. J Autoimmun. 2003 Dec;21(4):339-51
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory