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Gja1M1Jrt
Chemically induced Allele Detail
Nomenclature
Symbol: Gja1M1Jrt
Name: gap junction protein, alpha 1; mutation 1, Janet Rossant
MGI ID: MGI:2682016
Synonyms: Cx43G60S, Gja11Jrt, Gja1Jrt
Gene: Gja1  Location: Chr10:56377300-56390419 bp, + strand  Genetic Position: Chr10, 28.64 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThe mutation in was identified as GGT Glycine to AGT Serine (G 60 S) in the first extracellular loop. This Glycine is conserved in human, rat, cow, hamster, chick and zebrafish. (J:86757, J:101733)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 17 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gja1 Mutation:  35 strains or lines available
References
Original:  J:86757 Rossant J, ENU mutants from the Center of Modeling Human Disease. MGI Direct Data Submission. 2003;
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory