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Birc5tm1Vaux
Targeted Allele Detail
Nomenclature
Symbol: Birc5tm1Vaux
Name: baculoviral IAP repeat-containing 5; targeted mutation 1, David L Vaux
MGI ID: MGI:2681348
Synonyms: survivin-
Gene: Birc5  Location: Chr11:117849251-117855743 bp, + strand  Genetic Position: Chr11, 82.96 cM, cytoband E2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86384
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region except for the first 4 codons was replaced with a cassette containing lacZ followed by floxed neo. (J:86384)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Birc5 Mutation:  12 strains or lines available
References
Original:  J:86384 Uren AG, et al., Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr Biol. 2000 Nov 2;10(21):1319-28
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory