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Syn3tm1Pggd
Targeted Allele Detail
Nomenclature
Symbol: Syn3tm1Pggd
Name: synapsin III; targeted mutation 1, Paul Greengard
MGI ID: MGI:2675750
Synonyms: Syn3tm1Jfe, synapsin III -
Gene: Syn3  Location: Chr10:85890989-86334760 bp, - strand  Genetic Position: Chr10, 41.95 cM, cytoband C2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77048
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced exon 1. Western blot analysis on brain extracts derived from homozygous mice confirmed that no detectable protein was made from this allele. (J:77048)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Syn3 Mutation:  22 strains or lines available
References
Original:  J:77048 Feng J, et al., Regulation of neurotransmitter release by synapsin III. J Neurosci. 2002 Jun 1;22(11):4372-80
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory