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Med31l11Jus15
Chemically induced Allele Detail
Nomenclature
Symbol: Med31l11Jus15
Name: mediator complex subunit 31; lethal, Chr 11, Justice 15
MGI ID: MGI:2671886
Gene: Med31  Location: Chr11:72211724-72215592 bp, - strand  Genetic Position: Chr11, 43.93 cM, cytoband B4
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Mutagenesis for Dev. Defects
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a C to T mutation in exon 4 that is predicted to result in a truncation at amino acid 105 eliminating the last 26 amino acids. The absence of protein expression was confirmed by western blot analysis on embryo extracts. (J:161417)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Med31 Mutation:  6 strains or lines available
References
Original:  J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory