Erbb2^l11Jus8
Chemically induced Allele Detail

Summary

• Symbol: Erbb2^l11Jus8
• Name: erb-b2 receptor tyrosine kinase 2; lethal, Chr 11, Justice 8
• MGI ID: MGI:2671879
• Synonyms: l11Jus08
• Gene: Erbb2 Location: Chr11:98303310-98328542 bp, + strand Genetic Position: Chr11, 61.75 cM, cytoband D
• Alliance: Erbb2^l11Jus8 page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Mutagenesis for Dev. Defects

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to G point mutation that results in the amino acid susbtitution of arginine for methionine at position 802 (M802R). (J:222460)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Erbb2 Mutation: 59 strains or lines available

Notes

Additional non-causative mutations identified in l11Jus08 mice include: T to C in Med31, T to A in Nf1. J:222460

References

• Original: J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
• All: 5 reference(s)