Tg(HD82Gln)81Gschi
Transgene Detail
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Symbol: |
Tg(HD82Gln)81Gschi |
Name: |
transgene insertion 81, Gabriele Schilling |
MGI ID: |
MGI:2670626 |
Synonyms: |
HD-N171-82Q, N171-82Q, PrP-htt-N171-82Q, Tg(HD82Gln)81Dbo, TGN(HD82Gln)81Dbo |
Transgene: |
Tg(HD82Gln)81Gschi Location: unknown
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Alliance: |
Tg(HD82Gln)81Gschi page
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(HD82Gln)81Gschi expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
HTT (3064) |
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Mutation details: This transgenic line expresses an N-terminally truncated human huntingtin cDNA that encodes 82 glutamines and encompasses the first 171 amino acids. The altered huntingtin cDNA is under control of a mouse prion protein promoter, which drives transgene expression in the neurons of the central nervous system
(J:53797, J:99630)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:53797 Schilling G, et al., Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin [published erratum appears in Hum Mol Genet 1999 May;8(5):943]. Hum Mol Genet. 1999 Mar;8(3):397-407 |
All: |
84 reference(s) |
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