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Dclre1ctm1.1Fwa
Targeted Allele Detail
Nomenclature
Symbol: Dclre1ctm1.1Fwa
Name: DNA cross-link repair 1C; targeted mutation 1.1, Frederick W Alt
MGI ID: MGI:2667616
Synonyms: ArtL
Gene: Dclre1c  Location: Chr2:3424131-3464130 bp, + strand  Genetic Position: Chr2, 1.93 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:80995
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA single loxP site was left in place of exons 5 and 6 after the floxed neo cassette was removed from Dclre1ctm1Fwa ES cells via cre-mediated recombination. (J:80995)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dclre1c Mutation:  14 strains or lines available
References
Original:  J:80995 Rooney S, et al., Leaky scid phenotype associated with defective v(d)j coding end processing in artemis-deficient mice. Mol Cell. 2002 Dec;10(6):1379-90
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory