All Phenotypes Dclre1c<tm1.1Fwa> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dclre1c^tm1.1Fwa
targeted mutation 1.1, Frederick W Alt
MGI:2667616

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dclre1c^tm1.1Fwa/Dclre1c^tm1.1Fwa	involves: 129S6/SvEvTac * C57BL/6	MGI:2667619

Allelic Composition	Dclre1c^tm1.1Fwa/Dclre1c^tm1.1Fwa
Genetic Background	involves: 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dclre1c^tm1.1Fwa mutation (0 available); any Dclre1c mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

arrested B cell differentiation ( J:80995 )

• block at a progenitor stage when Ig rearrangements first occur

arrested T cell differentiation ( J:80995 )

• T cell development is partially blocked at the CD4-CD8- double negative progenitor stage when Tcr rearrangements first occur

immune system

arrested B cell differentiation ( J:80995 )

• block at a progenitor stage when Ig rearrangements first occur

arrested T cell differentiation ( J:80995 )

• T cell development is partially blocked at the CD4-CD8- double negative progenitor stage when Tcr rearrangements first occur

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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