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Targeted Allele Detail
Symbol: Pdgfratm11(EGFP)Sor
Name: platelet derived growth factor receptor, alpha polypeptide; targeted mutation 11, Philippe Soriano
MGI ID: MGI:2663656
Synonyms: alphaGFP, PdgfalphaGFP, PdgfalpharGFP, PdgfraH2B-GFP, PDGFRalphaEGFP, PdgfRalpha-H2B-GFP
Gene: Pdgfra  Location: Chr5:75152292-75198215 bp, + strand  Genetic Position: Chr5, 39.55 cM
Germline Transmission:  Earliest citation of germline transmission: J:83560
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsThe gene was disrupted by a knock-in vector consisting of an enhanced GFP fused with an human Hist2h2be gene (H2Be-GFP) for chromatin localization and a floxed PGK-neo cassette. (J:83560)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 159 assay results
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pdgfra Mutation:  14 strains or lines available
Original:  J:83560 Hamilton TG, et al., Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. Mol Cell Biol. 2003 Jun;23(11):4013-25
All:  134 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
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