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Targeted Allele Detail
Symbol: Bag4tm1Yeh
Name: BCL2-associated athanogene 4; targeted mutation 1, Wen-Chen Yeh
MGI ID: MGI:2663613
Synonyms: SODD-
Gene: Bag4  Location: Chr8:25764538-25785209 bp, - strand  Genetic Position: Chr8, 14.17 cM, cytoband A3
Germline Transmission:  Earliest citation of germline transmission: J:83559
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe gene was disrupted by replacement of exon 2 with a PGK-neo cassette via homologous recombination. Absence of gene expression was confirmed by Western blot analysis of primary embryonic fibroblasts derived from homozygous mutants. (J:83559)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bag4 Mutation:  25 strains or lines available
Original:  J:83559 Takada H, et al., Role of SODD in regulation of tumor necrosis factor responses. Mol Cell Biol. 2003 Jun;23(11):4026-33
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.15
The Jackson Laboratory