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Chrm5tm1Yeo
Targeted Allele Detail
Nomenclature
Symbol: Chrm5tm1Yeo
Name: cholinergic receptor, muscarinic 5; targeted mutation 1, John Yeomans
MGI ID: MGI:2661114
Synonyms: M5 KO
Gene: Chrm5  Location: Chr2:112479171-112480769 bp, - strand  Genetic Position: Chr2, 57.02 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83217
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe endogenous gene was disrupted by a neomycin selection cassette inserted by homologous recombination. The deleted region encoded a portion of the third intracellular loop. (J:83217)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Chrm5 Mutation:  26 strains or lines available
References
Original:  J:83217 Takeuchi J, et al., Increased drinking in mutant mice with truncated M5 muscarinic receptor genes. Pharmacol Biochem Behav. 2002 May;72(1-2):117-23
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory