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Fgfr1tm1.1Jpa
Targeted Allele Detail
Nomenclature
Symbol: Fgfr1tm1.1Jpa
Name: fibroblast growth factor receptor 1; targeted mutation 1.1, Juha Partanen
MGI ID: MGI:2657013
Synonyms: Fgfr1deltaflox
Gene: Fgfr1  Location: Chr8:25513654-25575714 bp, + strand  Genetic Position: Chr8, 14.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83004
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed region encompassing exons 8 through 15 was excised via cre-mediated recombination in the germline. (J:83004)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr1 Mutation:  171 strains or lines available
References
Original:  J:83004 Trokovic R, et al., FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. EMBO J. 2003 Apr 15;22(8):1811-23
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory