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Ackr1tm1Skmz
Targeted Allele Detail
Nomenclature
Symbol: Ackr1tm1Skmz
Name: atypical chemokine receptor 1 (Duffy blood group); targeted mutation 1, Kazuhisa Sekimizu
MGI ID: MGI:2656980
Gene: Ackr1  Location: Chr1:173331886-173333750 bp, - strand  Genetic Position: Chr1, 80.33 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82938
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of exon 1 and part of exon 2 with a neomycin resistant cassette via homologous recombination. (J:82938)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ackr1 Mutation:  8 strains or lines available
References
Original:  J:82938 Fukuma N, et al., A role of the Duffy antigen for the maintenance of plasma chemokine concentrations. Biochem Biophys Res Commun. 2003 Mar 28;303(1):137-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory