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Tfdp1tm1Lili
Targeted Allele Detail
Nomenclature
Symbol: Tfdp1tm1Lili
Name: transcription factor Dp 1; targeted mutation 1, Lili Yamasaki
MGI ID: MGI:2653309
Synonyms: Dp1-
Gene: Tfdp1  Location: Chr8:13338751-13378448 bp, + strand  Genetic Position: Chr8, 5.78 cM, cytoband A1-A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81580
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of exons 4-9 with a neomycin resistance cassette in the opposite orientation. The targeted mutation results in deletion of amino acids 66-330. Absence of gene expression in homozygous mutant E9.5 embryos was confirmed by Western blot analysis. (J:81580)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 25 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tfdp1 Mutation:  32 strains or lines available
References
Original:  J:81580 Kohn MJ, et al., Dp1 is required for extra-embryonic development. Development. 2003 Apr;130(7):1295-305
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory