About   Help   FAQ
Hes7tm1Kag
Targeted Allele Detail
Summary
Symbol: Hes7tm1Kag
Name: hes family bHLH transcription factor 7; targeted mutation 1, Ryoichiro Kageyama
MGI ID: MGI:2652222
Synonyms: Hes7-, Hes7tm1Rka
Gene: Hes7  Location: Chr11:69011230-69014881 bp, + strand  Genetic Position: Chr11, 42.38 cM
Alliance: Hes7tm1Kag page
Irregular sacral segmentation in Hes7tm1Kag/Hes7tm1Kag mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:72325
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn IRES-lacZ-PGK-neomycin resistance cassette replaced most of the coding region. In situ hybridization studies of whole mount E9.5 embryos did not detect transcript in homozygous mutant embryos. (J:72325)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Hes7 Mutation:  21 strains or lines available
References
Original:  J:72325 Bessho Y, et al., Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev. 2001 Oct 15;15(20):2642-7
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory