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Csnk2btm1.2Bb
Targeted Allele Detail
Nomenclature
Symbol: Csnk2btm1.2Bb
Name: casein kinase 2, beta polypeptide; targeted mutation 1.2, Brigitte Boldyreff
MGI ID: MGI:2450158
Synonyms: CK2Beta-
Gene: Csnk2b  Location: Chr17:35116196-35122053 bp, - strand  Genetic Position: Chr17, 18.59 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81637
Parent Cell Line:  AT1 (ES Cell)
Strain of Origin:  129S2/SvPasCrl
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA floxed fragment containing the promoter and exons 1 and 2 was excised via cre-mediated excision. Western blot analysis of heterozygous ES cell extracts indicated that protein was not produced from this allele. (J:81637)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csnk2b Mutation:  4 strains or lines available
References
Original:  J:81637 Buchou T, et al., Disruption of the regulatory Beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality. Mol Cell Biol. 2003 Feb;23(3):908-15
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory