About   Help   FAQ
Targeted Allele Detail
Symbol: Rag1tm1Bal
Name: recombination activating 1; targeted mutation 1, David Baltimore
MGI ID: MGI:2448994
Synonyms: Rag-1-
Gene: Rag1  Location: Chr2:101638282-101649501 bp, - strand  Genetic Position: Chr2, 53.88 cM
Premature death and kidney disease in C1galt1ptl1/C1galt1ptl1 and C1galt1ptl1/C1galt1ptl1 Rag1tm1Bal/Rag1tm1Bal mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:18049
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsThe gene was disrupted by insertion of a PGK-neo cassette into the coding region at amino acid 330 resulting in a frameshift mutation. (J:18049, J:92470)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Rag1 Mutation:  81 strains or lines available
Original:  J:18049 Spanopoulou E, et al., Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice. Genes Dev. 1994 May 1;8(9):1030-42
All:  76 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory