Tg(H2-K-Stat5b)1Wjl
Transgene Detail

Summary

• Symbol: Tg(H2-K-Stat5b)1Wjl
• Name: transgene insertion 1, Warren J Leonard
• MGI ID: MGI:2448073
• Synonyms: TG1
• Transgene: Tg(H2-K-Stat5b)1Wjl Location: unknown
• Alliance: Tg(H2-K-Stat5b)1Wjl page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-K-Stat5b)1Wjl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Stat5b (MGI:103035)

• Mutation details: The transgenic construct contained sequence encoding Stat5b driven by a H2-K promoter and followed by an IgH enhancer. Stat5b overexpression was verified in the thymus and spleen by Western blot analysis. Western blot analysis using a an anti-phospho-Stat5b antibody showed that the transgenic protein was phosphorylated upon Il2 stimulation. (J:80897)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:80897 Kelly J, et al., A role for stat5 in CD8(+) T cell homeostasis. J Immunol. 2003 Jan 1;170(1):210-7
• All: 5 reference(s)