Npy2r^tm1.1Hhz
Targeted Allele Detail

Summary

• Symbol: Npy2r^tm1.1Hhz
• Name: neuropeptide Y receptor Y2; targeted mutation 1.1, Herbert Herzog
• MGI ID: MGI:2447398
• Synonyms: Y2^-
• Gene: Npy2r Location: Chr3:82445690-82455391 bp, - strand Genetic Position: Chr3, 36.49 cM
• Alliance: Npy2r^tm1.1Hhz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77345
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele is derived from Npy2r^tm1Hhz. The floxed Npy2r gene was deleted by crossing Npy2r^tm1Hhz animals to cre deleter strain TgN(CMV-cre)1Cgn. Resulting progeny have a single loxP site in place of the Npy2r sequence. (J:77345)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npy2r Mutation: 30 strains or lines available

References

• Original: J:77345 Sainsbury A, et al., Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8938-43
• All: 41 reference(s)