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Juntm4Wag
Targeted Allele Detail
Nomenclature
Symbol: Juntm4Wag
Name: jun proto-oncogene; targeted mutation 4, Erwin F Wagner
MGI ID: MGI:2445420
Synonyms: c-junf, junf
Gene: Jun  Location: Chr4:95049036-95052222 bp, - strand  Genetic Position: Chr4, 43.34 cM, cytoband C5-C7
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75863
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe gene was flanked with a loxP site and a floxed neo-TK cassette via homologous recombination. The neo-TK cassette was removed in correctly targeted ES cells by transient expression of cre recombinase. The resulting mutation consists of Jun flanked by single loxP sites. (J:75863)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Jun Mutation:  7 strains or lines available
References
Original:  J:75863 Behrens A, et al., Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver. EMBO J. 2002 Apr 2;21(7):1782-90
All:  58 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory