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Tg(Vav-BCL2)1Jad
Transgene Detail
Nomenclature
Symbol: Tg(Vav-BCL2)1Jad
Name: transgene insertion 1, Jerry M Adams
MGI ID: MGI:2429387
Synonyms: Bcl20, hBcl-2 Tg, Vav2-hBcl-2, vav-bcl-2, vav-Bcl2, vav-bcl-2-69
Transgene: Tg(Vav-BCL2)1Jad  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Vav-BCL2)1Jad expresses 1 gene
 
Mutation detailsOverexpression of human BCL2 cDNA was driven by the mouse Vav promoter, which drove expression predominantly in nucleated cells of hematopoietic tissue. (J:59085)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:59085 Ogilvy S, et al., Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14943-8
All:  85 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory