About   Help   FAQ
Targeted Allele Detail
Symbol: F2rl1tm1Mslb
Name: coagulation factor II (thrombin) receptor-like 1; targeted mutation 1, Mary Stevens
MGI ID: MGI:2389587
Synonyms: F2rl1tm1Nwb, PAR-2-, PAR2ko
Gene: F2rl1  Location: Chr13:95511732-95525227 bp, - strand  Genetic Position: Chr13, 49.53 cM
Germline Transmission:  Earliest citation of germline transmission: J:79757
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsThe endogenous locus was disrupted by the insertion of a construct containing hygromycin and neomycin selection genes. Transcript was undetected by Northern blot analysis of liver tissue obtained from homozygous mutant mice. (J:79757)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any F2rl1 Mutation:  39 strains or lines available
Original:  J:79757 Schmidlin F, et al., Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway. J Immunol. 2002 Nov 1;169(9):5315-21
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.11
The Jackson Laboratory