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F2rl1tm1Mslb
Targeted Allele Detail
Nomenclature
Symbol: F2rl1tm1Mslb
Name: coagulation factor II (thrombin) receptor-like 1; targeted mutation 1, Mary Stevens
MGI ID: MGI:2389587
Synonyms: F2rl1tm1Nwb, PAR-2-, PAR2ko
Gene: F2rl1  Location: Chr13:95511732-95525240 bp, - strand  Genetic Position: Chr13, 49.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79757
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsThe endogenous locus was disrupted by the insertion of a construct containing hygromycin and neomycin selection genes. Transcript was undetected by Northern blot analysis of liver tissue obtained from homozygous mutant mice. (J:79757)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any F2rl1 Mutation:  36 strains or lines available
References
Original:  J:79757 Schmidlin F, et al., Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway. J Immunol. 2002 Nov 1;169(9):5315-21
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory