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Tg(Hsp70-1-cre)1Arge
Transgene Detail
Nomenclature
Symbol: Tg(Hsp70-1-cre)1Arge
Name: transgene insertion 1, Argiris Efstratiadis
MGI ID: MGI:2389571
Synonyms: Hs-cre1, Hspa1b-cre1
Transgene: Tg(Hsp70-1-cre)1Arge  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J x CBA
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsA sequence fragment from the murine Hsp70-1 locus encompassing 655 bp of the 5' flanking and noncoding sequence was adjoined to sequence encoding cre recombinase. Two tandem integrations of the transgenic construct were identified in the founder line. Transgene expression occurred early in embryogenesis, resulting in the production of progeny exhibiting complete recombination of reporter constructs. (J:60711)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Hspa1b     Summary of all recombinase alleles driven by Hspa1b. Comparative matrix view of recombinase activities
 

Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:60711 Dietrich P, et al., Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes. Mamm Genome. 2000 Mar;11(3):196-205
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory