Hoxd11^{tm2(Hoxd11)Mrc}
Targeted Allele Detail

Summary

• Symbol: Hoxd11^{tm2(Hoxd11)Mrc}
• Name: homeobox D11; targeted mutation 2, Mario R Capecchi
• MGI ID: MGI:2389125
• Gene: Hoxd11 Location: Chr2:74509902-74517360 bp, + strand Genetic Position: Chr2, 44.13 cM
• Alliance: Hoxd11^{tm2(Hoxd11)Mrc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:78766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A second copy of the Hoxd11 coding region and surrounding sequence was inserted at the endogenous locus. The construct also contained a floxed neomycin selection cassette. (J:78766)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd11 Mutation: 14 strains or lines available

References

• Original: J:78766 Boulet AM, et al., Duplication of the Hoxd11 gene causes alterations in the axial and appendicular skeleton of the mouse. Dev Biol. 2002 Sep 1;249(1):96-107
• All: 1 reference(s)