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Etv4tm1Arbr
Targeted Allele Detail
Summary
Symbol: Etv4tm1Arbr
Name: ets variant 4; targeted mutation 1, Silvia Arber
MGI ID: MGI:2387770
Synonyms: Etv4-, Etv4lacZ, Pea3nlslacZ, Pea3NLZ
Gene: Etv4  Location: Chr11:101660568-101676197 bp, - strand  Genetic Position: Chr11, 65.48 cM
Alliance: Etv4tm1Arbr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:78717
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA portion of exon 6 and all of exons 7 through 11 were replaced with a cassette containing IRES-NLS-lacZ followed by a polyadenylation signal and neo gene. (J:78717)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 17 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Etv4tm1Arbr
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Etv4 Mutation:  40 strains or lines available
References
Original:  J:78717 Livet J, et al., ETS gene Pea3 controls the central position and terminal arborization of specific motor neuron pools. Neuron. 2002 Aug 29;35(5):877-92
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory