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Tg(Cd4-cre)1Cwi
Transgene Detail
Nomenclature
Symbol: Tg(Cd4-cre)1Cwi
Name: transgene insertion 1, Christopher B Wilson
MGI ID: MGI:2386448
Synonyms: CD4cre, CD4-Cre, CD4-Cre+, CD4CRE, CD4-creTg, CD4p-Cre
Transgene: Tg(Cd4-cre)1Cwi  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsCre recombinase is expressed under the control of mouse Cd4 regulatory elements. The Cd4 enhancer, promoter and silencer collectively drive expression at sequential stages specifically of CD4+ T cell development. (J:73127)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cd4     Summary of all recombinase alleles driven by Cd4.
 

Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 6 strains available      Cell Lines: 0 lines available
References
Original:  J:73127 Lee PP, et al., A critical role for dnmt1 and DNA methylation in T cell development, function, and survival. Immunity. 2001 Nov;15(5):763-74
All:  426 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory