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Kat2btm1Roth
Targeted Allele Detail
Nomenclature
Symbol: Kat2btm1Roth
Name: K(lysine) acetyltransferase 2B; targeted mutation 1, Sharon Y Roth
MGI ID: MGI:2386280
Synonyms: Pcaf-
Gene: Kat2b  Location: Chr17:53566861-53672720 bp, + strand  Genetic Position: Chr17, 27.86 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65002
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe exon 376 bp downstream of the translational start site was replaced by a cassette containing a polyA signal followed by a PGK-neo. An absence of transcript in homozygous mutant mice was determined by Northern blot analysis of a variety of tissues. (J:65002)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kat2b Mutation:  123 strains or lines available
References
Original:  J:65002 Xu W, et al., Loss of gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat Genet. 2000 Oct;26(2):229-32
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory