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Mmp12tm1Sds
Targeted Allele Detail
Nomenclature
Symbol: Mmp12tm1Sds
Name: matrix metallopeptidase 12; targeted mutation 1, Steven D Shapiro
MGI ID: MGI:2386174
Synonyms: MME-, Mmp12-, MMP-12-
Gene: Mmp12  Location: Chr9:7344381-7369499 bp, + strand  Genetic Position: Chr9, 2.46 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:32902
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mmp12 Mutation:  6 strains or lines available
References
Original:  J:32902 Shipley JM, et al., Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice. Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):3942-6
All:  43 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory