About   Help   FAQ
Igh-Vtm1Jjk
Targeted Allele Detail
Summary
Symbol: Igh-Vtm1Jjk
Name: immunoglobulin heavy chain variable region; targeted mutation 1, James J Kenny
MGI ID: MGI:2385812
Synonyms: V1-
Gene: Igh-V  Location: unknown  Genetic Position: Chr12, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:62284
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 3.4 kb fragment of genomic DNA containing the Igh-V gene was replaced with a PGK-neo cassette via homologous recombination. (J:62284)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igh-V Mutation:  5 strains or lines available
References
Original:  J:62284 Mi QS, et al., Highly reduced protection against Streptococcus pneumoniae after deletion of a single heavy chain gene in mouse. Proc Natl Acad Sci U S A. 2000 May 23;97(11):6031-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory